Linked to dangerous aneurysms

NEW YORK (HealthDay News) — Eating red meat may increase the risk of abdominal aortic aneurysm (AAA), a serious condition that affects the blood vessels in the abdomen, a new study finds.

According to researchers, high levels of TMAO, a byproduct generated by intestinal bacteria after digesting animal products, are associated with an increased risk of developing this condition.

“AAA occurs when a bulge forms in the aorta, and if it ruptures, it can be fatal in up to 80% of cases outside the hospital,” the authors explained. The findings were published in JAMA Cardiology. Dr. Scott Cameron, chief of vascular medicine at the Cleveland Clinic, noted, “These results suggest that targeting TMAO levels could help prevent and treat aneurysmal disease beyond surgery.”

Currently, the only option for patients is stenting or surgery, as there are no predictive blood tests.

Researchers analyzed data from 237 Europeans and 658 Americans. “Our results showed that high blood levels of TMAO were associated with a more than threefold increased risk of AAA,” Cameron said.

Furthermore, the same marker was found to be associated with more than a twofold increased risk of rapidly growing aneurysms. “TMAO is produced by gut microbes, and levels are higher when eating animal products and red meat,” explained Dr. Stanley Hazen. He added, “Drugs targeting this pathway have been shown to block aneurysm development and rupture in preclinical models, but they are not yet available for humans.”

Hazen emphasized the importance of prevention: “It's vital to share these results because they show how crucial diet can be in the early treatment of aneurysms.”

Although further studies are still needed, experts recommend reducing red meat consumption and considering other risk factors such as age, smoking, and associated diseases.

At a glance

Hidden risk

Abdominal aortic aneurysms are often silent until they rupture. The lack of symptoms makes early detection difficult, making prevention and monitoring key health factors.

Dietary prevention

Reducing consumption of red meat and animal products can lower TMAO levels.